Testosterone therapy: Potential benefits and risks as you age
by Admin
Posted on 05-04-2023 06:51 PM
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4 we suggest against routinely prescribing testosterone therapy to all men 65 years of age or older with low testosterone concentrations (1∣⊕⊕oo). In men 65 years who have symptoms or conditions suggestive of testosterone deficiency (such as low libido or unexplained anemia) and consistently and unequivocally low morning testosterone concentrations, we suggest that clinicians offer testosterone therapy on an individualized basis after explicit discussion of the potential risks and benefits. (2∣⊕⊕oo).
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Hormone health network from the endocrine society
the endocrine society is the world’s largest and most influential organization of endocrinologists (doctors who treat hormone disorders). The hormone health network provides online resources for patients, including information on men’s health and low testosterone.
The site also contains an up-to-date physician referral directory with more than 6,500 endocrine society member doctors. American society for reproductive medicine
this society of fertility specialists maintains a patient-focused website with easy-to-read educational pages on reproductive health topics, including testosterone use and male infertility. The site also contains resources for finding a reproductive health professional. American urological association (aua)
the aua, which represents urologists and urologic health professionals, publishes guidelines on the diagnosis and treatment of testosterone deficiency.
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The influence of testosterone in men
Testosterone is considered a male sex hormone, and it is primarily produced in the testicles (although a very small amount comes from the adrenal glands). Women also have testosterone in their bodies but at much lower levels than men. Testosterone is responsible for the development of primary sexual characteristics: male genitalia. It is also responsible for secondary sexual characteristics including muscle bulk, deep voice, and hair pattern. Testosterone helps regulate other physical factors that impact mood and energy levels and protect heart health. It is also responsible for maintaining a normal sex drive. Testosterone helps to influence or provides: cardiovascular protection obesity.
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Nieschlag e, nieschlag s: endocrine history: the history of discovery, synthesis and development of testosterone for clinical use. Eur j endocrinol. 2019 jun 1;180(6):r201-r212. Doi: 10. 1530/eje-19-0071. [ article ] white cm, ferraro-borgida mj, moyna nm, mcgill cc, ahlberg aw, thompson pd, chow ms, heller gv: the pharmacokinetics of intravenous testosterone in elderly men with coronary artery disease. J clin pharmacol. 1998 sep;38(9):792-7. [ article ] wang c, catlin dh, starcevic b, leung a, distefano e, lucas g, hull l, swerdloff rs: testosterone metabolic clearance and production rates determined by stable isotope dilution/tandem mass spectrometry in normal men: influence of ethnicity and age.
Testosterone levels generally peak during adolescence and early adulthood. As you age, your testosterone level gradually declines — typically about 1% a year after age 30 or 40. For older men, it's important to determine if a low testosterone level is due to normal aging or if it is due to a disease (hypogonadism). Hypogonadism hampers the ability to produce normal amounts of testosterone due to a problem with the testicles or with the pituitary gland that controls the testicles. Testosterone replacement therapy, in the form of injections, pellets, patches or gels, can improve the signs and symptoms of low testosterone in these men.
The two charts below list the general normal ranges of testosterone based on age and sex. The level is measured in nanograms per deciliter (ng/dl). It’s important to note that the normal ranges for testosterone levels can vary based on the type of blood test done and the laboratory where it is done. Your provider will always reference your laboratory’s normal ranges when interpreting your results. Talk to them if you have questions. Normal testosterone levels for people assigned male at birth:.